What are Omega-3s?
Every membrane of every cell is comprised of a unique suite of fatty acids depending on the tissue type and each cell has a specific role to play in your body’s metabolism. The membrane must have certain physical characteristics, either very floppy and loose and or very stiff. These physical characteristics depend on the need of that cell and the fatty acid composition is unique to afford a certain kind of chemical flexibility. Omega-3 fatty acids (EPA and DHA) are the molecular building blocks that produce a specialized group of hormones known as resolvins and are key to the reduction of inflammation.
These anti-inflammatory hormones are critical factors in resolving inflammation throughout the body. Because it is often difficult to get suitable levels of Omega-3 in our diets, we tend to have inadequate concentrations of omega-3 fatty acids in the blood. As a result, it becomes impossible to generate appropriate levels of resolvins to create an optimal state to return the body to equilibrium after the introduction of inflammation. In a healthy system, Inflammation is how the body’s immune system wages combat against either an unwanted toxin or trauma. However, when that Inflammation persists and becomes Chronic, it is a key factor in weight gain, chronic disease, and aging more rapidly. Chronic cellular inflammation will result ff the inflammation grows too strong without an adequate resolution phase, however, without it, your body will begin waging war against your organs and systems.
Omega-3s are found most prominently in a variety of fish and fish oils and a diet rich in Omega-3s can combat inflammation that results from the presence of Omega-6 Fatty Acids. Omega 6s promote inflammation and are prominent in the American or “Western Diet” as they are associated with foods fried in corn oil, soybean oil, and safflower oil. The result is most Americans consume levels of foods high in Omega-3s and an abundance of foods high in Omega-6. To achieve adequate levels of resolvin formation, a healthy person will require a minimum of 2.5 grams per day of EPA and DHA. For those with an existing chronic inflammatory disease, the levels of EPA and DHA required can be considerably higher to increase the resolution of existing cellular inflammation.
Clinical Research Studies have demonstrated that the sharp increase in our obesity epidemic correlates to the increased intake of Omega-6s. Without a corresponding increase in Omega-3s, there is not an appropriate balance of both to minimize inflammation and promote overall wellness.
We conduct a blood test that can be done to demonstrate the percentages EPA, DHA, total saturates, total monounsaturates, etc. in the red blood cell membranes. The deviation between the ranges are not vast and most people will fall within the statistical ranges regardless of how much they are eating. However, they can fall at very different ends of those ranges (between 20-30% differences would be high). Interestingly, there is a much wider variation in the fatty acids we eat than what we see in our blood because the body is making the membranes from the raw materials that we eat and your body determines where it want fatty acids to be sent. Therefore you can only influence your levels by what you eat to a limited extent.
Health Benefits of Omega-3s
There are a multitude of benefits resulting from a diet rich in Omega 3s:
- Prediabetes and Diabetes
- Athletic Performance
- Behavior and Mood
- Brain Health
- Heart Health
- Pre/Postnatal Health
- Joint disease
Which Omega-3s Are Important for Health?
The primary benefit of Omega-3s is its ability to resolve inflammation. Clinical Research Studies have focused on two Omega-3s to record their clinical benefits pertaining to decreased inflammation: EPA (Eicosapentaenoic Acid) and DHA (Docosahexaenoic Acid). Both EPA and DHA are found primarily in fish and fish oil.
EPA helps minimize the formation of pro-inflammatory hormones (i.e. eicosanoids) while both EPA and DHA help manufacture hormones critical to resolving inflammation (i.e. resolvins).
The 2:1 ratio of EPA to DHA has been scientifically demonstrated to produce the widest range of health benefits.
Why Fish Oils for Omega-3s and not Krill Oil, Flaxseed or Other Omega-3 Products?
Dr. Deepti recommends her patients consume a minimum of 3000 mg of EPA and DHA daily for wellness and to reduce inflammation. To get the most beneficial results and the highest intake you need purified Omega-3 fish oil rather than consuming fish alone. However, not all fish oils are the same. Krill oil is often advertised for its benefits and often considered because it is typically a lower-cost alternative. However, Krill oil is not fish oil but is made of crustaceans (small shrimp). The process of harvesting and extracting krill oil involves the use of harmful chemicals (acetone and hexane). Flaxseed is a vegetarian source of the Omega-3 alpha-linolenic acid (ALA). Flaxseed oil is only beneficial if it is converted into EPA and DHA and the conversion process is very inefficient resulting in only about 1-10%. You would, therefore, need to increase your consumption to large quantities of flaxseed oil to yield the same benefits like a far smaller quantity EPA and DHA rich fish oil.
What is different about our Omega-3s?
Dr. Deepti spent several months sourcing a fish oil manufacturer who offers the highest levels of purity. While all fish oil products are comprised of the same raw materials (sardines and anchovies), the distinction between them is their purification., Polychlorinated Biphenyls (PCBs) are highly toxic industrial compounds that have been banned from manufacture in the United States since 1977. However, because PCBs are slow to break down and can persist in the environment at dangerous levels, they are also the most difficult toxins to remove from fish oil. Dr. Deepti’s standards for PCBs are far more stringent than pharmaceutical dietary supplement standards and she sources only the highest International Fish Oil Standards (IFOS) products.
The health benefits of Omega-3s is delivered through the total amount of EPA and DHA contained within the oils. We carry two fish oil products at all times:
- Our Omega 3 contains 1000mg of pure Omega 3 per dose (400mg of EPA and 200mg of DHA)
- Our Omega 3 Ultimate contains 3000mg of Fish Oil with 1400mg of pure Omega 3 per dose (1200 mg of EPA and 600 mg of DHA)
When you purchase an Omega-3 fatty acid product it’s imperative to review the cost per gram of EPA and DHA. There are plenty of companies advertising Omega-3s, however, our different products have some of the lowest cost per gram of EPA and DHA of any fish oil product on the market. Furthermore, the highest purity standards and freshness.
Dr. Deepti has dedicated almost 20 years of research on the impact of diet and Omega-3s on inflammation and hormonal response. She has introduced thousands of patients to the vast benefits of Omega-3s and has played a critical role in sourcing the manufacturing, purification, and stabilization of high potency and purity Omega-3 products.
What are Polyphenols?
Polyphenols have effects that are positively correlated to the doses ingested. At low doses (approximately 0.5 grams per day) they can activate gene transcription factors that increase the synthesis of anti-oxidative enzymes to cause a reduction in oxidative stress. At elevated levels (approximately 1.0 grams per day) polyphenols activate anti-inflammatory gene transcription factors acting as inflammatory inhibitors, reducing the likelihood of inflammation initiating. At the most elevated doses (approximately 1.5 grams per day) polyphenols activate a gene that increases the production of AMP kinase that controls cellular metabolism.
Some of the most popular foods and beverages that are rich in polyphenols are dark chocolate, red wine, and berries. However, there are many common and not so common foods that have a high concentration which includes:
|Fruits||Vegetables||Nuts and seeds||Herbs and spices||Other|
|grapes||red lettuce||walnuts||curry powder||ginger|
|grapefruit||red onions||dried basil||green tea|
|lemon||yellow onions||Legumes||dried marjoram||olives and olive oil|
|nectarines||spinach||black beans||dried parsley||grapeseed oil|
|peaches||shallots||tofu||dried peppermint||red wine|
|pears||soybean sprouts||dried spearmint||vinegar|
|pomegranate||Grains||soy meat||lemon verbena|
|strawberries||whole wheat||white beans||sage|